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Hormone Testing
Hormones are chemical messengers that regulate nearly every function in the body — from metabolism and mood to reproductive health, energy, and sleep. Even subtle imbalances can lead to a wide range of symptoms, often dismissed or misattributed.
Common Signs & Symptoms of Hormonal Imbalance
In Women:
- Irregular or painful periods
- PMS or PMDD
- Fatigue, brain fog
- Anxiety or depression
- Weight gain (especially belly)
- Acne or skin changes
- Hair loss or thinning
- Low libido
- Infertility
- Hot flashes or night sweats (even in younger women)
In Men:
- Low energy, motivation
- Decreased muscle mass
- Erectile dysfunction
- Low libido
- Weight gain
- Irritability or depression
- Gynecomastia (breast tissue growth)
- Hair thinning
In All Genders:
- Sleep disturbances
- Mood swings
- Poor stress tolerance
- Unexplained weight changes
- Thyroid symptoms (cold hands/feet, hair thinning, dry skin)
- Blood sugar issues (crashes, carb cravings)
Hormone Testing: When and What to Test
If you’re experiencing any of the above symptoms, hormone testing may be warranted — especially if:
- Symptoms are persistent or cyclical
- You’re over age 30, when hormones begin to decline
- You’ve had chronic stress, illness, or inflammation
- You’re taking medications that could affect hormones (e.g., birth control, steroids)
- You have a family history of hormonal disorders
Common Assessments for Hormone Imbalance
Sex Hormones
Hormone | Role | Imbalance Signs |
|---|---|---|
Estrogen (E2) | Female reproductive health, mood | PMS, heavy periods, fibroids, hot flashes |
Progesterone | Balances estrogen, supports mood | Anxiety, insomnia, PMS, irregular periods |
Testosterone | Muscle mass, libido, mood (in all sexes) | Fatigue, low sex drive, weight gain |
DHEA-S | Precursor to sex hormones | Low energy, low mood, aging signs |
LH / FSH | Regulate ovulation and sperm production | Cycle irregularity, infertility |
Thyroid Hormones
Hormone | Role | Imbalance Signs |
|---|---|---|
TSH | Stimulates thyroid gland | Fatigue, weight changes |
Free T4 & Free T3 | Metabolism, mood, energy | Hair loss, brain fog |
Reverse T3 | Inactive thyroid hormone (stress marker) | Hypothyroid symptoms with “normal” labs |
Thyroid antibodies (TPO, TGAb) | Autoimmune thyroid disorders | Hashimoto’s, Graves’ |
Adrenal (Stress) Hormones
Hormone | Role | Imbalance Signs |
|---|---|---|
Cortisol | Stress response, energy | Fatigue, insomnia, weight gain, anxiety |
Cortisone | Inactive form of cortisol | Helps assess stress axis function |
ACTH | Signals cortisol production | Chronic stress, fatigue |
Other Metabolic Hormones
Hormone | Role | Imbalance Signs |
|---|---|---|
Insulin | Blood sugar regulation | Crashes, cravings, weight gain |
Leptin | Hunger & satiety signaling | Appetite dysregulation, weight gain |
Adiponectin | Anti-inflammatory, insulin sensitizing | Low in obesity, diabetes |
Growth Hormone / IGF-1 | Tissue repair, muscle mass | Fatigue, poor recovery, aging signs |
Types of Hormone Testing
Test Type | Best For | Pros & Cons |
|---|---|---|
Blood (serum) | Thyroid, total sex hormones, insulin, oral hormone replacement therapy evaluation | Widely available, reliable for some hormones |
Saliva | Cortisol rhythm, free sex hormones, topical hormone replacement therapy (cream) evaluation | Non-invasive, good for adrenal & bioavailable hormones |
Urine (DUTCH test) | Hormone metabolites, cortisol curve, estrogens | Best for functional hormone analysis |
Dried Blood Spot | At-home finger prick testing | Convenient, moderate accuracy |
